Antimicrobial activity of cobalt bis(dicarbollide) aminoderivatives

0463789 - ÚACH 2017 RIV CZ eng C - Conference Paper (international conference)
Kvasničková, E. - Masák, J. - Šícha, Václav
Antimicrobial activity of cobalt bis(dicarbollide) aminoderivatives.
Proceedings of the 3rd International Conference on Chemical Technology, ICCT 2015. Prague: Czech Society of Industrial Chemistry, 2015 - (Kalenda, P.; Lubojacký, J.), s. 466-471. ICCT. ISBN 978-80-86238-82-1.
[International Conference on Chemical Technology-ICCT2015/3./. Mikulov (CZ), 13.04.2015-15.04.2015]
Institutional support: RVO:61388980
Keywords : cobalt bis(dicarbollide) * aminoderivatives * antimicrobial activity
Subject RIV: CA - Inorganic Chemistry

We carried out experiments focused on the determination of the antimicrobial acitivity of selected representatives of cobalt bis{dicarbollide) aminoderivates. lt was proved, that studied yeast strain C. parapsilosis DBM 2165 is not sensitive to the cobalt bis{dicarbollide) or its aminoderivatives. Gram-negative bacteria P. aeruginosa B-59188 is weakly susceptive to cobalt bis(dicarbollide), but no significant inhibition of growth by cobalt bis(dicarbollide) aminoderivatives was observed. The highest effect on inhibition of microbial growth was confirmed in the case of gram-positive bacteria 5. aureus. This observation demonstrates the real possibility of using these substances in the treatment of infection caused by gram-positive bacterial strains.
Permanent Link: http://hdl.handle.net/11104/0262945