Design of porphyrin-based conjugated microporous polymers with enhanced singlet oxygen productivity

0460327 - ÚACH 2017 RIV GB eng J - Journal Article
Hynek, Jan - Rathouský, Jiří - Demel, Jan - Lang, Kamil
Design of porphyrin-based conjugated microporous polymers with enhanced singlet oxygen productivity.
RSC Advances. Roč. 6, č. 50 (2016), s. 44279-44287. E-ISSN 2046-2069
R&D Projects: GA ČR(CZ) GA16-15020S
Institutional support: RVO:61388980 ; RVO:61388955
Keywords : Conjugated microporous polymers * Crystalline materials * Metal organic framework * biomimetic catalysis
Subject RIV: CA - Inorganic Chemistry; CF - Physical ; Theoretical Chemistry (UFCH-W)
Impact factor: 3.108, year: 2016

Novel non-toxic materials with antimicrobial surfaces are needed for medicinal applications. Potential alternatives for bacterial inactivation include materials that produce singlet oxygen, O-2((1)Delta(g)), a short-lived, highly oxidative, and cytotoxic species. We synthesized a promising group of materials, porphyrin-based conjugated microporous polymers (CMPs), which effectively generate O-2((1)Delta(g)) under visible light irradiation. CMPs were rationally designed and synthesized to maximize O-2((1)Delta(g)) production. A strategy based on three-dimensional frameworks allowed the immediate environment of the porphyrin units to be tuned and their structure-property relationships to be elucidated. We investigated the photophysical and photochemical properties of the frameworks and compared them with the properties of porphyrin-based CMPs and metal-organic frameworks. In general, the O-2((1)Delta(g)) production activity of the CMPs correlated with neither the surface area nor with the pore volume. The novel CMPs displayed high O-2((1)Delta(g)) production, were stable in organic solvents, and did not undergo measurable photobleaching.
Permanent Link: http://hdl.handle.net/11104/0260434