Tuning of polymeric nanoparticles by coassembly of thermoresponsive polymers and a double hydrophilic thermoresponsive block copolymer

0460133 - ÚMCH 2017 RIV US eng J - Journal Article
Zhang, Q. - Voorhaar, L. - Filippov, Sergey K. - Yesil, B. F. - Hoogenboom, R.
Tuning of polymeric nanoparticles by coassembly of thermoresponsive polymers and a double hydrophilic thermoresponsive block copolymer.
Journal of Physical Chemistry B. Roč. 120, č. 20 (2016), s. 4635-4643. ISSN 1520-6106. E-ISSN 1520-5207
R&D Projects: GA ČR(CZ) GC15-10527J
Institutional support: RVO:61389013
Keywords : nanoparticles * thermoresponsive polymers * self-assembly
Subject RIV: CF - Physical ; Theoretical Chemistry
Impact factor: 3.177, year: 2016

The coassembly behavior of thermoresponsive statistical copolymers and a double hydrophilic block copolymer having a permanently hydrophilic block and a thermoresponsive block is investigated. By adjusting the hydrophilicity of the thermoresponsive statistical copolymers, hybrid nanoparticles are obtained with various ratios of the two species. Importantly, the size of these nanoparticles can be controlled in between 40 and 250 nm dependent on the TCP and the amount of statistical copolymers in the solution. Simultaneous analysis of static and dynamic light scattering data indicates that the possible structure of nanoparticles varies from hard sphere to less compact architecture and most probably depends on a difference between cloud point temperatures of individual components. This developed coassembly method provides a simple platform for the preparation of defined polymeric nanoparticles.
Permanent Link: http://hdl.handle.net/11104/0260270