Polypseudorotaxanes between .alpha.-cyclodextrin and poly(propylene glycol)-b-poly(ethylene glycol)-b-poly(propylene glycol) copolymers studied by MALDI-TOF mass spectrometry

0456042 - ÚMCH 2017 RIV GB eng J - Journal Article
Horský, Jiří - Walterová, Zuzana
Polypseudorotaxanes between .alpha.-cyclodextrin and poly(propylene glycol)-b-poly(ethylene glycol)-b-poly(propylene glycol) copolymers studied by MALDI-TOF mass spectrometry.
European Polymer Journal. Roč. 74, January (2016), s. 256-263. ISSN 0014-3057. E-ISSN 1873-1945
Grant - others:OPPK(XE) CZ.2.16/3.1.00/24504
Institutional support: RVO:61389013
Keywords : polypseudorotaxanes * reverse pluronics * cyclodextrin
Subject RIV: CD - Macromolecular Chemistry
Impact factor: 3.531, year: 2016

MALDI-TOF mass spectrometry is used to show that formation of solid polypseudorotaxanes between alpha-cyclodextrin (alpha-CD) and poly(propylene glycol)–poly(ethylene glycol)–poly(propylene glycol) block copolymers (PPG–PEG–PPG, Reverse Pluronics) is a block length selective process. A comparison of copolymer composition matrices of neat Reverse Pluronics 10R5 and 17R4 and of the copolymers in their precipitated complexes with alpha-CD shows that the distribution with respect to an absolute PPG content is not affected by the complexation, which means that complexation occurs with Reverse Pluronics generally, not just with the fraction of copolymers with at least one outer block short or completely absent and that alpha-CD can slide even over block of 20 PG. Nevertheless, the complexation is a selective process with respect to PEG as copolymers with shorter PEG blocks are more abundant in the supernatant while the content of PPG remains almost unchanged for both Reverse Pluronics.
Permanent Link: http://hdl.handle.net/11104/0256641