A comparison of portal vein embolization with poly(2-hydroxyethylmethacrylate) and a histoacryl/lipiodol mixture in patients scheduled for extended right hepatectomy

0455921 - ÚMCH 2016 RIV CZ eng J - Journal Article
Peregrin, J. H. - Janoušek, R. - Kautznerová, D. - Oliverius, M. - Sticová, E. - Přádný, Martin - Michálek, Jiří
A comparison of portal vein embolization with poly(2-hydroxyethylmethacrylate) and a histoacryl/lipiodol mixture in patients scheduled for extended right hepatectomy.
Physiological Research. Roč. 64, č. 6 (2015), s. 841-848. ISSN 0862-8408. E-ISSN 1802-9973
R&D Projects: GA ČR(CZ) GA13-00939S
Institutional support: RVO:61389013
Keywords : extended right hepatectomy * portal vein embolization * embolization-induced left liver lobe hypertrophy
Subject RIV: FH - Neurology
Impact factor: 1.643, year: 2015
http://www.biomed.cas.cz/physiolres/2015/6_15.htm

To determine whether PHEMA [poly(2-hydroxyethylmethacrylate)] is suitable for portal vein embolization in patients scheduled to right hepatectomy and whether it is as effective as the currently used agent (a histoacryl/lipiodol mixture). Two groups of nine patients each scheduled for extended right hepatectomy for primary or secondary hepatic tumor, had right portal vein embolization in an effort to induce future liver remnant (FLR) hypertrophy. One group had embolization with PHEMA, the other one with the histoacryl/lipiodol mixture. In all patients, embolization was performed using the right retrograde transhepatic access. Embolization was technically successful in all 18 patients, with no complication related to the embolization agent. Eight patients of either group developed FLR hypertrophy allowing extended right hepatectomy. Likewise, one patient in each group had recanalization of a portal vein branch. Histology showed that both embolization agents reach the periphery of portal vein branches, with PHEMA penetrating somewhat deeper into the periphery. PHEMA has been shown to be an agent suitable for embolization in the portal venous system comparable with existing embolization agent (histoacryl/lipiodol mixture).
Permanent Link: http://hdl.handle.net/11104/0256531