0449230 - FGÚ 2016 RIV GB eng J - Journal Article
Musílková, Jana - Kotelnikov, Ilya - Novotná, Katarína - Pop-Georgievski, Ognen - Rypáček, František - Bačáková, Lucie - Proks, Vladimír
Cell adhesion and growth enabled by biomimetic oligopeptide modification of a polydopamine-poly(ethylene oxide) protein repulsive surface.
Journal of Materials Science-Materials in Medicine. Roč. 26, č. 11 (2015), s. 253. ISSN 0957-4530. E-ISSN 1573-4838
R&D Projects: GA ČR(CZ) GAP108/11/1857; GA ČR(CZ) GAP108/12/1168; GA MŠMT(CZ) EE2.3.30.0029; GA MŠMT(CZ) ED1.1.00/02.0109
Institutional support: RVO:67985823 ; RVO:61389013
Keywords : protein repulsive surface * cell adhesion * RGD * endothelial cells
Subject RIV: EI - Biotechnology ; Bionics; CD - Macromolecular Chemistry (UMCH-V)
Impact factor: 2.272, year: 2015
DOI: https://doi.org/10.1007/s10856-015-5583-3

In this study, protein–repulsive polydopamine-poly(ethylene oxide) (PDA-PEO) surfaces were functionalized with an RGD-containing peptide (RGD), with a collagen-derived peptide binding fibronectin (Col), or by a combination of these peptides (RGD + Col, ratio 1:1) in concentrations of 90 fmol/cm2 and 700 fmol/cm2 for each peptide type. A combination of RGD + Col seems to be the most promising for surface modification of biomaterials, e.g. vascular prostheses

Permanent Link: http://hdl.handle.net/11104/0250821