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Melatonin administered during the fetal stage affects circadian clock in the suprachiasmatic nucleus but not in the liver
- 1.0443146 - FGÚ 2016 RIV US eng J - Journal Article
Houdek, Pavel - Polidarová, Lenka - Nováková, Marta - Matějů, Kristýna - Kubík, Štěpán - Sumová, Alena
Melatonin administered during the fetal stage affects circadian clock in the suprachiasmatic nucleus but not in the liver.
Developmental Neurobiology. Roč. 75, č. 2 (2015), s. 131-144. ISSN 1932-8451. E-ISSN 1932-846X
R&D Projects: GA ČR(CZ) GAP303/12/1108
Institutional support: RVO:67985823
Keywords : ontogenesis * circadian system * suprachiasmatic nuclei * clock gene * melatonin
Subject RIV: FH - Neurology
Impact factor: 2.529, year: 2015
The aim of the study was to ascertain the role of maternal melatonin in entrainment of the fetal circadian clocks. The role of maternal melatonin in the entrainment of fetal circadian clocks has been suggested, but direct evidence was lacking. The data demonstrate that in pregnant rats with suppressed endogenous melatonin levels, application of melatonin affects the fetal clock in the SCN but not in the liver
Permanent Link: http://hdl.handle.net/11104/0245901
Number of the records: 1