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Using Anthraquinone Labeled Nucleotide Triphosphates for Electrochemical Analysis of DNA

  1. 1.
    0440910 - BFÚ 2015 CZ eng H - Proceedings (Czech conference)
    Vidláková, Pavlína - Balintová, Jana - Horáková Brázdilová, Petra - Havran, Luděk - Orság, Petr - Fojta, Miroslav - Hocek, Michal
    Using Anthraquinone Labeled Nucleotide Triphosphates for Electrochemical Analysis of DNA.
    2011. 4 s.
    [31st International Conference on Modern Electrochemical Methods. Jetrichovice (CZ), 23.05.2011-27.05.2011]
    Keywords : DNA * Anthraquinone * Electrochemical analysis
    Subject RIV: BO - Biophysics; CC - Organic Chemistry (UOCHB-X)

    Base-modified anthraquinone-nucleotide triphosphates were used for DNA labeling. Anthraquinone modified nucleotides were incorporated into DNA by primer extension with KOD polymerase. In cyclic and square wave voltammetry at HMDE or PGE antraquinone gave a well developed characteristic signal suitable for differentiation of the labeled DNA from unlabeled one.
    Permanent Link: http://hdl.handle.net/11104/0244015

     
     
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