Two-dimensional condensation of 5-fluorocytosine at the mercury electrode

0440812 - BFÚ 2015 RIV GB eng J - Journal Article
Fojt, Lukáš - Doneux, T. - Vetterl, Vladimír
Two-dimensional condensation of 5-fluorocytosine at the mercury electrode.
Electrochimica acta. Roč. 73, SI (2012), s. 141-144. ISSN 0013-4686. E-ISSN 1873-3859
R&D Projects: GA ČR(CZ) GAP205/10/2378; GA MŠMT(CZ) LC06035
Institutional support: RVO:68081707
Keywords : 2D condensation * Hanging mercury drop electrode * 5-Fluorocytosine
Subject RIV: BO - Biophysics
Impact factor: 3.777, year: 2012

Adsorption and two-dimensional (2D) condensation of 5-fluotocytosine on hanging mercury drop electrode is studied in this work. 5-fluorocytosine is an important derivative of cytosine which is widely used in pharmacology. The influence of concentration, temperature pH and electrolyte composition on the 2D condensation of 5-fluorocytosine was investigated by differential capacitance measurements. Three capacitance pits associated with the formation of 2D compact layers are evidenced. One film, formed at potential slightly negative from the potential of zero charge of the electrode, involves both neutral and protonated 5-fluorocytosine molecules. At highly negatively charged electrodes, dipole-induced orientation of 5-fluorocytosine leads to the formation of two additional 2D layers. One of them is found to result from the interaction of 5-fluorocytosine with acetic acid, present in the buffer electrolyte.
Permanent Link: http://hdl.handle.net/11104/0243960