Number of the records: 1
Does Folic Acid Supplementation Rescue Defects in ECE-1-Deficient Mouse Embryos?
- 1.0438439 - FGÚ 2015 RIV CZ eng J - Journal Article
Haque, A. - Šaňková, Barbora - Kvasilová, A. - Krejčí, Eliška - Sedmera, David
Does Folic Acid Supplementation Rescue Defects in ECE-1-Deficient Mouse Embryos?
Folia Biologica. Roč. 60, č. 5 (2014), s. 243-251. ISSN 0015-5500. E-ISSN 0015-5500
R&D Projects: GA ČR(CZ) GAP302/11/1308; GA ČR(CZ) GA13-12412S
Institutional support: RVO:67985823
Keywords : endothelin-converting enzyme * mice * endothelin 1 * cardiac malformations * endothelin receptor
Subject RIV: EA - Cell Biology
Impact factor: 1.000, year: 2014
Endothelin signalling is essential for normal embryonic development. Disruption of this pathway leads to defects in the development of subsets of cranial and cephalic neural crest derivatives. Here we demonstrate that folic acid supplementation is not able to rescue the phenotype in a mouse model of endothelin converting enzyme deficiency
Permanent Link: http://hdl.handle.net/11104/0241865
Number of the records: 1