0437660 - FGÚ 2015 RIV US eng J - Journal Article
Eckhardt, Adam - Jágr, Michal - Pataridis, Statis - Mikšík, Ivan
Proteomic Analysis of Human Tooth Pulp: Proteomics of Human Tooth.
Journal of Endodontics. Roč. 40, č. 12 (2014), s. 1961-1966. ISSN 0099-2399. E-ISSN 1878-3554
R&D Projects: GA ČR(CZ) GA13-17224S; GA ČR(CZ) GAP206/12/0453; GA MZd(CZ) NT14324
Institutional support: RVO:67985823
Keywords : dentin * human pulp * tandem mass spectrometry * tooth proteome * 2-dimensional gel electrophoresis
Subject RIV: FF - HEENT, Dentistry
Impact factor: 3.375, year: 2014 ; AIS: 0.626, rok: 2014
DOI: https://doi.org/10.1016/j.joen.2014.07.001

A total of 342 proteins were identified with high confidence, and 2 proteins were detected for the first time in an actual human sample. The identified tooth pulp proteins have a variety of functions: structural, catalytic, transporter, protease activity, immune response, and many others. In a comparison with dentin and blood plasma, 140 (pulp/dentin) shared proteins were identified, 37 of which were not observed in plasma. It can be suggested that they might participate in the unique pulp-dentin complex
Permanent Link: http://hdl.handle.net/11104/0241189