Chemical Engineering Methods and Technology

0436778 - ÚEM 2015 US eng M - Monography Chapter
Hejčl, Aleš - Jendelová, Pavla - Syková, Eva
ADULT BONE MARROW STEM CELLS AND BIOCOMPATIBLE POLYMERS IN SCI REPAIR.
Chemical Engineering Methods and Technology. New York: NOVA SCIENCE PUBLISHERS, 2009 - (Stein D. B.), s. 689-712. ISBN 978-1-60741-702-6
Institutional support: RVO:68378041
Keywords : spinal cord injury * hydrogel * tissue engineering
Subject RIV: FH - Neurology

Hydrogels were used as 3D carriers for stem cells and implanted into acute spinal cord lesions. Various hydrogels are suitable as carriers of MSCs and/or other stem cells, as the cells survived in the hydrogels for several months. Further, these hydrogel constructs (hydrogel+MSCs) were also tested in an animal model of chronic SCI. The hydrogel constructs seeded with MSCs created a successful bridge, preventing tissue atrophy and improving functional outcome.
Permanent Link: http://hdl.handle.net/11104/0240447