0435625 - ÚEM 2017 RIV DE eng J - Journal Article
Ouda, Ladislav - Burianová, Jana - Balogová, Zuzana - Lu, H. P. - Syka, Josef
Structural changes in the adult rat auditory system induced by brief postnatal noise exposure.
Brain Structure and Function. Roč. 221, č. 1 (2016), s. 617-629. ISSN 1863-2653. E-ISSN 1863-2661
R&D Projects: GA ČR(CZ) GCP303/11/J005; GA ČR(CZ) GAP303/12/1347; GA ČR(CZ) GBP304/12/G069
Institutional support: RVO:68378041
Keywords : noise exposure * critical period * central auditory system
Subject RIV: FH - Neurology
Impact factor: 4.698, year: 2016 ; AIS: 1.681, rok: 2016
DOI: https://doi.org/10.1007/s00429-014-0929-z

In this study, we analyze on the basis of the Golgi-Cox method the morphology of neurons in the IC, the medial geniculate body (MGB) and the auditory cortex (AC) of 3-month-old Long-Evans rats exposed to identical noise at postnatal day 14 and compare the results to littermate controls. In rats exposed to noise as pups, the mean total length of the neuronal tree was found to be larger in the external cortex and the central nucleus of the IC and in the ventral division of the MGB. Our findings demonstrate that early postnatal short noise exposure can induce permanent changes in the development of neurons in the central auditory system, which apparently represent morphological correlates of functional plasticity.
Permanent Link: http://hdl.handle.net/11104/0258950