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Getting it right before transplantation: example of a stem cell model with regenerative potential for the CNS
- 1.0435204 - ÚEM 2015 RIV CH eng J - Journal Article
Viero, C. - Forostyak, Oksana - Syková, Eva - Dayanithi, Govindan
Getting it right before transplantation: example of a stem cell model with regenerative potential for the CNS.
Frontiers in Cell and Developmental Biology. -, č. 2 (2014), s. 36. ISSN 2296-634X. E-ISSN 2296-634X
R&D Projects: GA ČR GAP304/11/2373; GA ČR(CZ) GAP304/11/0184; GA ČR(CZ) GBP304/12/G069; GA MŠMT EE2.3.20.0274
Institutional support: RVO:68378041
Keywords : human embryonic stem sell * neural precursors * neurodegenerative diseases
Subject RIV: FH - Neurology
We gather results from our previous studies and present a cell model that was successfully used in functional analyses and engraftment experiments. These neuronal precursors exhibit spontaneous and evoked activity, indicating that their electrophysiological and calcium handling properties are similar to those of matured neurons. Hence this summarized information will serve as a basis to design better stem cell-based therapies to improve neural regeneration.
Permanent Link: http://hdl.handle.net/11104/0241902
Number of the records: 1