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Interaction of antidepressant drug fluoxetine with the metabolism of triiodothyronine
- 1.0432122 - FGÚ 2015 GR eng C - Conference Paper (international conference)
Pavelka, Stanislav
Interaction of antidepressant drug fluoxetine with the metabolism of triiodothyronine.
Proceedings of the 7th International Symposium on Trace Elements in Human: New Perspectives. Athens: University of Athens, 2009, s. 178-184.
[International Symposium on Trace Elements in Human : New Perspectives /7./. Athens (GR), 13.10.2009-15.10.2009]
R&D Projects: GA ČR(CZ) GA304/08/0256
Institutional research plan: CEZ:AV0Z50110509
Keywords : antidepressant drug * metabolism * thyroid hormone
Subject RIV: ED - Physiology
In the present study, we followed the effects of subchronic administration (for 25 days) of antidepressant drug fluoxetine, alone or in combination with 3,5,3’-triiodothyronine (T3), on the metabolism of thyroid hormones in the rat. For this reason, we used radiometric enzyme assays for iodothyronine sulfotransferases (ST) and UDP-glucuronyltransferase (GT), as well as our newly developed radiometric assays for iodothyronine deiodinases of types 1, 2 and 3 (D1, D2 and D3).
Permanent Link: http://hdl.handle.net/11104/0236606
Number of the records: 1