Electrochemistry of Flavonolignans and their Interactions with DNA and Proteins

0431386 - ÚFCH JH 2015 RIV CZ eng C - Conference Paper (international conference)
Pyszková, M. - Zatloukalová, M. - Biedermann, David - Křen, Vladimír - Ulrichová, J. - Ramešová, Šárka - Sokolová, Romana - Vacek, J.
Electrochemistry of Flavonolignans and their Interactions with DNA and Proteins.
Sborník přednášek mezinárodní odborné konference XXXIV. Moderní Elektrochemické Metody. Ústí nad Labem: Best Servis, 2014 - (Navrátil, T.; Fojta, M.; Pecková, K.), s. 148-152. ISBN 978-80-905221-2-1.
[Moderní Elektrochemické Metody /34./. Jetřichovice (CZ), 19.05.2014-23.05.2014]
Institutional support: RVO:61388955 ; RVO:61388971
Keywords : Flavonolignan * Silymarin * Oxidation
OECD category: Physical chemistry; Biochemistry and molecular biology (MBU-M)

Electrochemical oxidation of flavonolignans silybin, silydianin, silychristin and their 2,3-dehydroderivatives, was studied using ex situ and in situ cyclic and square wave voltammetry at pyrolytic graphite electrode. The pilot results presented here could be used for further investigation of mechanism of oxidation and reactivity of flavonolignans to DNA and proteins.
Permanent Link: http://hdl.handle.net/11104/0235929