Capillary electrophoresis applied to chiral analysis of helquats and characterization of their intermediates and interconversion barriers using randomly and single isomer sulfated cyclodextrins as stereoselectors

0430043 - ÚOCHB 2015 CZ eng C - Conference Paper (international conference)
Kašička, Václav - Koval, Dušan - Sázelová, Petra - Severa, Lukáš - Vávra, Jan - Adriaenssens, Louis - Sonawane, Manoj R. - Teplý, Filip
Capillary electrophoresis applied to chiral analysis of helquats and characterization of their intermediates and interconversion barriers using randomly and single isomer sulfated cyclodextrins as stereoselectors.
Acta Universitatis Palackianae Olomucensis. Facultas Rerum Naturalium. Chemica 51S. Olomouc: Palacký University, 2014 - (Maier, V.; Ševčík, J.), s. 50-51. ISBN 978-80-244-3950-1. ISSN 0232-0061.
[Advances in Chromatography and Electrophoresis & Chiranal 2014. Olomouc (CZ), 10.02.2014-14.02.2014]
R&D Projects: GA ČR(CZ) GAP206/12/0453; GA ČR(CZ) GA13-17224S; GA ČR GA13-32974S
Institutional support: RVO:61388963
Keywords : helquats * chiral analysis * capillary electrophoresis
Subject RIV: CB - Analytical Chemistry, Separation

Capillary electrophoresis in acidic sodium phosphate background electrolyte, pH 2.4, with randomly sulfated alfa-, beta- and gamma-cyclodextrins as chiral selectors was applied to fast, high-resolution separation of enantiomers of a series of 35 helquats, a new class of N-heteroaromatic dicationic helicene-like species. The developed methodology was employed for evaluation of preparative enantioresolution procedures of helquats, for monitoring their racemization and for determination of interconversion barrier of helquat enantiomers.
Permanent Link: http://hdl.handle.net/11104/0235362