Conformation analysis of nucleoside analogues containing selenium and tellurium in five-membered pseudosugar ring

0429056 - ÚOCHB 2015 CZ eng C - Conference Paper (international conference)
Poštová Slavětínská, Lenka - Pohl, Radek - Rejman, Dominik
Conformation analysis of nucleoside analogues containing selenium and tellurium in five-membered pseudosugar ring.
Chemistry of Nucleic Acid Components. 16th Symposium. Praha: Institute of Organic Chemistry and Biochemistry AS CR, v. v. i, 2014 - (Hocek, M.), s. 354-355. Collection Symposium Series, 14. ISBN 978-80-86241-50-0.
[Symposium on Chemistry of Nucleic Acid Components /16./. Český Krumlov (CZ), 08.06.2014-13.06.2014]
R&D Projects: GA ČR GA13-24880S
Institutional support: RVO:61388963
Keywords : nucleoside analogues * five-membered pseudosugar ring * NMR
Subject RIV: CC - Organic Chemistry

The conformation analysis of synthetized thymine and adenosine nucleoside analogues with selenium and tellurium in five-membered pseudosugar ring has been studied. The experimental NMR measurement was complemented with DFT molecular modeling studies. It was found, that ratio between individual conformers in solution depends on the nature of the heteroatom in the five-membered pseudosugar ring.
Permanent Link: http://hdl.handle.net/11104/0234444