0427743 - FGÚ 2015 RIV US eng J - Journal Article
Vodička, Martin - Ergang, Peter - Mikulecká, Anna - Řeháková, Lenka - Klusoňová, Petra - Makal, J. - Soták, Matúš - Musílková, Jana - Zach, P. - Pácha, Jiří
Regulation of 11 beta-Hydroxysteroid Dehydrogenase Type 1 and 7 alpha-Hydroxylase CYP7B1 during Social Stress.
PLoS ONE. Roč. 9, č. 2 (2014), e89421. ISSN 1932-6203. E-ISSN 1932-6203
R&D Projects: GA ČR(CZ) GAP303/10/0969
Grant - others:Univerzita Karlova(CZ) Prvouk P34; Univerzita Karlova(CZ) 5366/2012
Institutional support: RVO:67985823
Keywords : 11beta-hydroxysteroid dehydrogenase * stress * HPA axis
Subject RIV: ED - Physiology
Impact factor: 3.234, year: 2014

The data show that social stress induces changes in enzymes of local metabolism of glucocorticoids (11HSD1, CYP7B1)in lymphoid organs and in brain structures associated with the regulation of the HPA axis. It is concluded that 11HSD1 might play a role in modulation of glucocorticoid feedback of the HPA axis during stress
Permanent Link: http://hdl.handle.net/11104/0233236