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Recent progress in the genetics of spontaneously hypertensive rats
- 1.0427697 - FGÚ 2015 RIV CZ eng J - Journal Article
Pravenec, Michal - Křen, Vladimír - Landa, Vladimír - Mlejnek, Petr - Musilová, Alena - Šilhavý, Jan - Šimáková, Miroslava - Zídek, Václav
Recent progress in the genetics of spontaneously hypertensive rats.
Physiological Research. Roč. 63, Suppl.1 (2014), S1-S8. ISSN 0862-8408. E-ISSN 1802-9973
R&D Projects: GA MŠMT(CZ) LL1204; GA MŠMT(CZ) LH12061; GA ČR(CZ) GAP303/10/0505; GA ČR(CZ) GAP301/10/0290; GA ČR(CZ) GAP301/12/0696; GA TA ČR(CZ) TA02010013; GA MŠMT(CZ) LH11049; GA ČR(CZ) GA13-04420S; GA MZd(CZ) NT14325
Institutional support: RVO:67985823
Keywords : spontaneously hypertensive rats * genetics * hypertension * left ventricular hypertrophy
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 1.293, year: 2014
The spontaneously hypertensive rat (SHR) is the most widely used animal model of essential hypertension and accompanying metabolic disturbances. Recent advances in sequencing of genomes of BN-Lx and SHR progenitors of the BXH/HXB recombinant inbred (RI) strains as well as accumulation of multiple data sets of intermediary phenotypes in the RI strains, as well as in manipulation of the rat genome will enable identification genetic determinants at the molecular level
Permanent Link: http://hdl.handle.net/11104/0233194
Number of the records: 1