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Pregnenolone sulfate activates NMDA receptor channels
- 1.0423161 - FGÚ 2014 RIV CZ eng J - Journal Article
Adamusová, Eva - Cais, Ondřej - Vyklický, Vojtěch - Kudová, Eva - Chodounská, Hana - Horák, Martin - Vyklický ml., Ladislav
Pregnenolone sulfate activates NMDA receptor channels.
Physiological Research. Roč. 62, č. 6 (2013), s. 731-736. ISSN 0862-8408. E-ISSN 1802-9973
R&D Projects: GA ČR(CZ) GBP304/12/G069; GA ČR(CZ) GAP303/12/1464; GA ČR(CZ) GAP303/11/0075; GA TA ČR(CZ) TE01020028; GA MŠMT(CZ) ED1.1.00/02.0109
Institutional support: RVO:67985823 ; RVO:61388963
Keywords : neurosteroids * pregnenolone sulfate * calcium imaging
Subject RIV: ED - Physiology; CC - Organic Chemistry (UOCHB-X)
Impact factor: 1.487, year: 2013
This article shows that pregnenolone sulfate, an endogenously occurring neurosteroid, is not only an allosteric modulator of NMDA receptors but also an endogenous NMDA agonist that activates GluN1/GluN2A-B receptors
Permanent Link: http://hdl.handle.net/11104/0229360
Number of the records: 1