0422537 - ÚPT 2014 US eng C - Conference Paper (international conference)
Starčuk jr., Zenon - Starčuková, Jana - Starčuk, Zenon
Short dual-band VAPOR-like pulse sequence for simultaneous water and lipid suppression for in vivo MR spectroscopy and spectroscopic imaging.
Proceedings of International Society for magnetic Resonance in Medicine. Vol. 19. Berkeley: International Society for Magnetic Resonance in Medicine, 2011, s. 149.
[International Society for Magnetic Resonance Scientific Meeting /19./ and Exhibition and the Society for Magnetic Resonance Technologists Annual Meeting /20./. Montreal (CA), 07.05.2011-13.05.2011]
R&D Projects: GA ČR GA102/09/1861
Institutional support: RVO:68081731
Keywords : VAPOR * pulse sequence * lipid * warwe * suppression
Subject RIV: BH - Optics, Masers, Lasers

The strong water and lipid content is a common problem in both clinical and research applications of short echo time in vivo proton MR spectroscopy and, especially, MR spectroscopic imaging. Their magnetization is overwhelming in comparison with the observed resonances of metabolites and is the major source of spectrum contamination from outside the volume of interest; the respective frequency bands are notorious for irreproducible artifacts, which may adversely affect spectral quantitation. For these reasons, various techniques have been developed to suppress such signals. To eliminate water, sequences of optimized water selective radiofrequency pulses interleaved with delays containing crusher gradients and preceding the localizing excitation are used most often. With such construction, the presaturation and excitation parts of the sequence are independent, and even very short echo times can be achieved. Among such methods, WET and VAPOR are the ones used most widely. The original VAPOR, developed primarily for single-voxel MRS, uses up to 8 CHESS RF pulses and long interpulse delays. It has been predicted recently that much shorter VAPOR-like sequences containing only 5 RF pulses (quick-VAPOR) and using very short interpulse delays can also even better performance if the flip angles and pulse widths are optimized. For brain measurements, lipid suppression is often based on the knowledge of the fat distribution geometry and outer volume suppression (OVS) is used for this purpose. Here we present experimental results of quick-VAPOR and suggest a very short dual-band VAPOR-like sequence applying the same construction method for water and lipids simultaneously.
Permanent Link: http://hdl.handle.net/11104/0228669