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Synthesis of alkylcarbonate analogs of O-acetyl-ADP-ribose
- 1.0399579 - ÚEB 2014 RIV GB eng J - Journal Article
Dvořáková, Marcela - Nencka, Radim - Dejmek, Milan - Zborníková, Eva - Březinová, Anna - Přibylová, Marie - Pohl, Radek - Migaud, M. E. - Vaněk, Tomáš
Synthesis of alkylcarbonate analogs of O-acetyl-ADP-ribose.
Organic & Biomolecular Chemistry. Roč. 11, č. 34 (2013), s. 5702-5713. ISSN 1477-0520. E-ISSN 1477-0539
Institutional support: RVO:61389030 ; RVO:61388963
Keywords : DEACETYLASES * FURANOSIDES * METABOLITE
Subject RIV: CC - Organic Chemistry
Impact factor: 3.487, year: 2013
The non-hydrolyzable alkylcarbonate analogs of O-acetyl-ADP-ribose have been synthesized from the phosphorylated ribose derivatives after coupling with AMP morpholidate promoted by mechanical grinding. The analogs were assessed for their ability to inhibit the human sirtuin homolog SIRT1.
Permanent Link: http://hdl.handle.net/11104/0226914
Název souboru Staženo Velikost Komentář Verze Přístup 2013_Dvorakova_ORGANIC & BIOMOLECULAR CHEMISTRY_5702.pdf 8 352.7 KB Jiná povolen
Number of the records: 1