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Inhibition of c-Jun N-terminal kinase (JNK) suppresses porcine oocyte ageing in vitro
- 1.0398779 - ÚEM 2014 RIV CZ eng J - Journal Article
Sedmíková, M. - Petr, J. - Dörflerová, A. - Nevoral, J. - Novotná, Božena - Krejčová, T. - Chmelíková, E. - Tůmová, L.
Inhibition of c-Jun N-terminal kinase (JNK) suppresses porcine oocyte ageing in vitro.
Czech Journal of Animal Science. Roč. 58, č. 12 (2013), s. 535-545. ISSN 1212-1819. E-ISSN 1805-9309
Grant - others:CIGA(CZ) 20122034; GAGA(CZ) 20122038
Institutional support: RVO:68378041
Keywords : MAPK * DNA fragmentation * apoptosis
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 0.871, year: 2013
JNK inhibitor supresses apoptosis and DNA fragmentation of aged oocytes and improves their embryonic development following the parthenogenetic activation (i.e., increases the percentage of parthenogenetically activated oocytes and the percentage of oocytes at morula stage after seven days of cultivation).
Permanent Link: http://hdl.handle.net/11104/0226178
Number of the records: 1