Coordination of auxin and ethylene biosynthesis by the aminotransferase VAS1

0396718 - ÚEB 2014 RIV US eng J - Journal Article
Zheng, Z.Y. - Guo, Y.X. - Novák, Ondřej - Dai, X.H. - Zhao, Y.D. - Ljung, K. - Noel, J.P. - Chory, J.
Coordination of auxin and ethylene biosynthesis by the aminotransferase VAS1.
Nature Chemical Biology. Roč. 9, č. 4 (2013), s. 244-246. ISSN 1552-4450. E-ISSN 1552-4469
R&D Projects: GA AV ČR KAN200380801
Institutional research plan: CEZ:AV0Z50380511
Keywords : PLANT DEVELOPMENT * SHADE AVOIDANCE * ARABIDOPSIS
Subject RIV: EC - Immunology
Impact factor: 13.217, year: 2013

We identify an Arabidopsis pyridoxal-phosphate-dependent aminotransferase, VAS1, whose loss-of-function simultaneously increases amounts of the phytohormone auxin and the ethylene precursor 1-aminocyclopropane-1-carboxylate. VAS1 uses the ethylene biosynthetic intermediate methionine as an amino donor and the auxin biosynthetic intermediate indole-3-pyruvic acid as an amino acceptor to produce L-tryptophan and 2-oxo-4-methylthiobutyric acid. Our data indicate that VAS1 serves key roles in coordinating the amounts of these two vital hormones.
Permanent Link: http://hdl.handle.net/11104/0224489