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Effects of sesquiterpene, flavonoid and coumarin types of compounds from Artemisia annua L. on production of mediators of angiogenesis
- 1.0396697 - ÚEM 2014 RIV PL eng J - Journal Article
Zhu, X. X. - Yang, L. - Li, Y. J. - Zhang, D. - Chen, Y. - Kostecká, Petra - Kmoníčková, Eva - Zídek, Zdeněk
Effects of sesquiterpene, flavonoid and coumarin types of compounds from Artemisia annua L. on production of mediators of angiogenesis.
Pharmacological Reports. Roč. 65, č. 2 (2013), s. 410-420. ISSN 1734-1140. E-ISSN 2299-5684
R&D Projects: GA MŠMT(CZ) ME10116
Institutional support: RVO:68378041
Keywords : sesquiterpenes * flavonoids * immunosuppression
Subject RIV: FR - Pharmacology ; Medidal Chemistry
Impact factor: 2.165, year: 2013
Flavonoids isolated from the medicinal herb Artemisia annua, casticin and chrysosplenol D, inhibit the major mediators of angiogenesis prostaglandin E2, nitric oxide and cytokines. Sesquiterpenes artemisinin, dihydroartemisinin, artemisinic acid, and artennuin B reduce the production of prostaglandin E2 solely.
Permanent Link: http://hdl.handle.net/11104/0224443
Number of the records: 1