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Evc Regulates a Symmetrical Response to Shh Signaling in Molar Development
- 1.0396271 - ÚEM 2014 RIV US eng J - Journal Article
Nakatomi, M. - Hovořáková, Mária - Gritli-Linde, A. - Blair, H. J. - MacArthur, K. - Peterka, Miroslav - Lesot, H. - Peterková, Renata - Ruiz-Perez, V. L. - Goodship, J. A. - Peters, H.
Evc Regulates a Symmetrical Response to Shh Signaling in Molar Development.
Journal of Dental Research. Roč. 92, č. 3 (2013), s. 222-228. ISSN 0022-0345. E-ISSN 1544-0591
R&D Projects: GA ČR GA304/09/1579; GA ČR(CZ) GAP305/12/1766
Institutional support: RVO:68378041
Keywords : odontogenesis * organogenesis * embryonic and fetal development
Subject RIV: EA - Cell Biology
Impact factor: 4.144, year: 2013
The observed growth abnormalities eventually manifest in first molar microdontia, disruption of molar segmentation and symmetry, root fusions, and delayed differentiation. Analysis of our data indicates that both spatially and temporally disrupted activities of the Shh pathway are the primary cause for the variable dental anomalies seen in patients with Ellis-van Creveld syndrome or Weyers acrodental dysostosis.
Permanent Link: http://hdl.handle.net/11104/0224108
Number of the records: 1