Number of the records: 1
Derivatives of valproic acid are active against pentetrazol-induced seizures in immature rats
- 1.0395566 - FGÚ 2014 RIV NL eng J - Journal Article
Mareš, Pavel - Kubová, Hana - Hen, N. - Yagen, B. - Bialer, M.
Derivatives of valproic acid are active against pentetrazol-induced seizures in immature rats.
Epilepsy Research. Roč. 106, 1-2 (2013), s. 64-73. ISSN 0920-1211. E-ISSN 1872-6844
R&D Projects: GA ČR(CZ) GAP304/10/1274; GA ČR(CZ) GBP304/12/G069
Institutional research plan: CEZ:AV0Z50110509
Institutional support: RVO:67985823
Keywords : experimental seizures * anticonvulsant action * derivatives of valproic acid * immature rats
Subject RIV: FH - Neurology
Impact factor: 2.190, year: 2013
The most common antiepileptic drug valproic acid has serious side effects (teratogenicity, hepatotoxicity). Its derivatives which are devoiod of these side effects were tested in immature rats and exhibited much stronger anticonvulsant action than the parent drug
Permanent Link: http://hdl.handle.net/11104/0223581
Number of the records: 1