2-Methacryloyloxyethyl phosporylcholine-functionalized monolithic silica capillary columns for hydrophilic interaction liquid chromatography

0395397 - ÚIACH 2014 HU eng A - Abstract
Moravcová, Dana - Planeta, Josef - Kahle, Vladislav - Karásek, Pavel - Roth, Michal
2-Methacryloyloxyethyl phosporylcholine-functionalized monolithic silica capillary columns for hydrophilic interaction liquid chromatography.
9th Balaton Symposium on High-Performance Separation Methods. Veszprém: Hungarian Society for Separation Sciences, 2013. s. 102. ISBN 978-963-89335-2-2.
[Balaton Symposium on High-Performance Separation Methods /9./. 04.09.2013-06.09.2013, Siofók]
R&D Projects: GA ČR(CZ) GAP206/11/0138; GA MV VG20112015021
Institutional support: RVO:68081715
Keywords : hilic * capillary chromatography * nucleotide
Subject RIV: CB - Analytical Chemistry, Separation

The zwitterionic silica-based monolithic columns (0.1 mm × 150 mm) containing phosphorylcholine functional groups were successfully synthesized by grafting of 2-methacryloyloxyethyl phosphorylcholine to the monolithic silica. These columns are designed especially for separation of negatively charged compounds, e.g., nucleosides, nucleotides and organic acids, by hydrophilic interaction chromatography.
Permanent Link: http://hdl.handle.net/11104/0223414