Evaluation of anti-inflammatory activity of selected legumes from Pakistan: In vitro inhibition of Cyclooxygenase-2

0395052 - ÚEB 2014 RIV PK eng J - Journal Article
ZIA-UL-HAQ, M. - Landa, Přemysl - Kutil, Zsófia - QAYUM, M. - Ahmad, S.
Evaluation of anti-inflammatory activity of selected legumes from Pakistan: In vitro inhibition of Cyclooxygenase-2.
Pakistan Journal of Pharmaceutical Sciences. Roč. 26, č. 1 (2013), s. 185-187. ISSN 1011-601X
Institutional research plan: CEZ:AV0Z50380511
Keywords : Anti-inflammatory * legumes * COX-2
Subject RIV: EF - Botanics
Impact factor: 0.950, year: 2013
http://www.pjps.pk/wp-content/uploads/pdfs/CD-PJPS-26-1-13/Paper-27.pdf

Crude methanolic extracts of selected legumes namely, black gram (Vigna mungo L.), green gram (Vigna radiata (L.) R. Wilczek), soybean (Glycine max (L.) Men.) and lentil (Lens culinaris Medik.) were investigated for anti-inflammatory effects, using COX-2 producing PGE(2) inhibitory assay. Percentage inhibition observed was 73.93, 79.84, 92.17 and 74.47 for black gram, green gram, soybean and lentil respectively at 20 mu g/ml extract concentration. The 100 mu g/ml concentration showed increase in the percent inhibition except for soybean. This is the first report on COX-2 inhibitory potential of food legumes.
Permanent Link: http://hdl.handle.net/11104/0223214