Polydopamine-modified nanocrystalline diamond thin films as a platform for bio-sensing applications

0394931 - ÚMCH 2014 RIV CH eng J - Journal Article
Pop-Georgievski, Ognen - Neykova, Neda - Proks, Vladimír - Houdková, Jana - Ukraintsev, Egor - Zemek, Josef - Kromka, Alexander - Rypáček, František
Polydopamine-modified nanocrystalline diamond thin films as a platform for bio-sensing applications.
Thin Solid Films. Roč. 543, 30 September (2013), s. 180-186. ISSN 0040-6090. E-ISSN 1879-2731.
[International Conference on NANO-structures self-assembly - NANOSEA 2012 /4./. S. Margherita di Pula - Sardinie, 25.06.2012-29.06.2012]
R&D Projects: GA ČR GAP108/11/1857; GA ČR(CZ) GBP108/12/G108
Grant - others:ČVUT(CZ) SGS10/297/OHK4/3T/14
Institutional support: RVO:61389013 ; RVO:68378271
Keywords : nanocrystalline diamond films * NCD * polydopamine
Subject RIV: CD - Macromolecular Chemistry; BM - Solid Matter Physics ; Magnetism (FZU-D)
Impact factor: 1.867, year: 2013

Diamond exhibits good biocompatibility and a large electrochemical potential window, and thus, it is particularly suitable for bio-functionalization and bio-sensing. Modification of the diamond surface can be achieved through mussel-inspired surface chemistry based on polydopamine (PDA) while maintaining the intrinsic properties of the surface. We present a comparative study on the polymerization/deposition of PDA from an aqueous solution of dopamine on hydrogen- (H) and oxygen- (O) terminated nanocrystalline diamond films (NCD). The dopamine polymerization/deposition was performed under mild conditions, which resulted in a confluent PDA layer. A detailed investigation of the growth kinetics of the PDA film on H- and O-terminated NCD substrates was performed using spectroscopic ellipsometry. The chemical composition, the functional group distribution, the surface topography and the wetting properties of the adherent PDA films were evaluated using X-ray photoelectron spectroscopy, atomic force microscopy and water contact angle goniometry, respectively. According to the results, a PDA layer can be used as a platform for future bio-functionalization and/or optical bio-sensing applications.
Permanent Link: http://hdl.handle.net/11104/0224739