Number of the records: 1
Molecular Mechanism of preQ(1) Riboswitch Action: A Molecular Dynamics Study
- 1.0389524 - BFÚ 2013 RIV US eng J - Journal Article
Banáš, Pavel - Sklenovský, P. - Wedekind, J.E. - Šponer, Jiří - Otyepka, Michal
Molecular Mechanism of preQ(1) Riboswitch Action: A Molecular Dynamics Study.
Journal of Physical Chemistry B. Roč. 116, č. 42 (2012), s. 12721-12734. ISSN 1520-6106. E-ISSN 1520-5207
R&D Projects: GA ČR(CZ) GD203/09/H046; GA ČR(CZ) GA203/09/1476; GA ČR(CZ) GAP208/12/1878; GA ČR(CZ) GBP305/12/G034
Grant - others:GA ČR(CZ) GBP208/12/G016
Program: GB
Institutional support: RVO:68081707
Keywords : HEPATITIS-DELTA VIRUS * PARTICLE MESH EWALD * SAM-II RIBOSWITCH
Subject RIV: BO - Biophysics; BO - Biophysics (BFU-R)
Impact factor: 3.607, year: 2012
Riboswitches often occur in the 5'-untranslated regions of bacterial mRNA where they regulate gene expression. The preQ(1) riboswitch controls the biosynthesis of a hyper-modified nucleoside queuosine in response to binding the queuosine metabolic intermediate. Structures of the ligand-bound and ligand-free states of the preQ(1) riboswitch from Thermoanaerobacter tengcongensis were determined recently by X-ray crystallography.
Permanent Link: http://hdl.handle.net/11104/0218381
Number of the records: 1