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Radiometric quantification of thyrotoxic and goitrogenic effects of exogenous bromide and perchlorate ions
- 1.0389389 - FGÚ 2013 RIV SK eng C - Conference Paper (international conference)
Pavelka, Stanislav
Radiometric quantification of thyrotoxic and goitrogenic effects of exogenous bromide and perchlorate ions.
Zborník prednášok – z vedeckého sympózia - Priemyselná toxikológia 2012. Bratislava: Slovenská technická univerzita, 2012, s. 152-156. ISBN 978-80-227-3722-7.
[Priemyselná toxikológia 2012 /32./. Svit, Vysoké Tatry (SK), 20.06.2012-22.06.2012]
R&D Projects: GA ČR(CZ) GA304/08/0256
Institutional research plan: CEZ:AV0Z50110509
Keywords : bromide * perchlorate * radiometric assay * thyroid peroxidase
Subject RIV: ED - Physiology
Correct assay conditions for the radiometric determination of the enzyme activity of thyroid peroxidase (TPO) have been established. With the use of the radiometric assay, we found that the influence of exogenous bromide on the TPO activity in the rat thyroids was biphasic, in relation to the extent of bromide intake in the animals. In contrast, in all the rats that were administered with high amounts of perchlorate were found elevated TPO activities
Permanent Link: http://hdl.handle.net/11104/0218289
Number of the records: 1