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Xenobiotic fluoxetine interacts with the metabolism of thyroid hormones
- 1.0389387 - FGÚ 2013 RIV SK eng C - Conference Paper (international conference)
Pavelka, Stanislav - Tribulová, N. - Soukup, Tomáš
Xenobiotic fluoxetine interacts with the metabolism of thyroid hormones.
Zborník prednášok – z vedeckého sympózia - Priemyselná toxikológia 2012. Bratislava: Slovenská technická univerzita, 2012, s. 139-143. ISBN 978-80-227-3722-7.
[Priemyselná toxikológia 2012 /32./. Svit, Vysoké Tatry (SK), 20.06.2012-22.06.2012]
R&D Projects: GA ČR(CZ) GA304/08/0256
Institutional research plan: CEZ:AV0Z50110509
Keywords : antidepressant drug * fluoxetine * iodothyronine deiodinase * thyroid hormone
Subject RIV: ED - Physiology
With the use of our newly elaborated and adapted radiometric enzyme assays for iodothyronine deiodinases and uridine 5‘-diphospho-glucuronyltransferase, we were able to quantify the effects of subchronic administration of xenobiotic fluoxetine, alone or in combination with 3,5,3’-triiodothyronine, on the metabolism of thyroid hormones in the rats
Permanent Link: http://hdl.handle.net/11104/0218288
Number of the records: 1