Capillary electrophoretic chiral analysis and estimation of helix inversion barrier of helquats using randomly sulfated cyclodextrins as chiral selectors

0387038 - ÚOCHB 2013 CZ eng C - Conference Paper (international conference)
Kašička, Václav - Koval, Dušan - Sázelová, Petra - Severa, Lukáš - Adriaenssens, Louis - Vávra, Jan - Teplý, Filip
Capillary electrophoretic chiral analysis and estimation of helix inversion barrier of helquats using randomly sulfated cyclodextrins as chiral selectors.
Acta Universitatis Palackianae Olomucensis. Facultas Rerum Naturalium. Chemica 50S. Olomouc: Faculty of Science, Palacký University Olomouc, 2012 - (Maier, V.; Ševčík, J.), s. 58-59. ISBN 978-80-244-3115-4. ISSN 0232-0061.
[International Symposium Advances in Chromatography and Electrophoresis and Chiranal. Olomouc (CZ), 11.06.2012-14.06.2012]
R&D Projects: GA ČR GAP207/10/2391; GA ČR(CZ) GA203/08/1428; GA ČR(CZ) GAP206/12/0453
Institutional support: RVO:61388963
Keywords : helquat chiral analysis * capillary electrophoresis * sulfated cyclodextrins
Subject RIV: CB - Analytical Chemistry, Separation

Capillary electrophoresis in acidic sodium phosphate background electrolyte, pH 2.4, with randomly sulfated alpha-, beta- and gamma-cyclodextrins as chiral selectors was employed for fast, high-resolution separation of enantiomers of a series of 24 helquats, a new class of N-heteroaromatic dicationic helicene-like species. The developed CE methodology will be utilized in the further investigation of helquats, e.g., in evaluation of their preparative enantioresolution procedures, in monitoring of their racemization and determination of interconversion barrier of helquat enantiomers.
Permanent Link: http://hdl.handle.net/11104/0216659