Sensor based on Förster resonance energy transfer with quantum dot

0386275 - ÚIACH 2013 RIV CZ eng C - Conference Paper (international conference)
Lišková, Marcela - Datinská, Vladimíra - Klepárník, Karel - Foret, František
Sensor based on Förster resonance energy transfer with quantum dot.
CECE 2012. 9th International Interdisciplinary Meeting on Bioanalysis. Brno: Ústav analytické chemie AV ČR, v. v. i, 2012 - (Foret, F.; Křenková, J.; Guttman, A.; Klepárník, K.; Boček, P.), s. 303-306. ISBN 978-80-904959-1-3.
[CECE 2012. International Interdisciplinary Meeting on Bioanalysis /9./. Brno (CZ), 01.11.2012-02.11.2012]
R&D Projects: GA ČR(CZ) GAP301/11/2055; GA ČR GAP206/11/2377; GA MŠMT(CZ) EE2.3.20.0182; GA ČR GA203/08/1680
Institutional research plan: CEZ:AV0Z40310501
Keywords : Förster resonance energy transfers * cells * quantum dots
Subject RIV: CB - Analytical Chemistry, Separation

Förster resonance energy transfers (FRET) are based on the nonradiative transfer of energy between a donor and acceptor dye in the distance 1-10 nm. With respect to this, quantum dots (QDs) with a high absorbance can serve as suitable donors of energy in FRET. Here, we present architectures of two sensors based on QD conjugates useful in imaging and diagnostics of cancer. One sensor, based on an oligonucleotide conjugate, can be used for the detection of complementary oligonucletide chains. The other was designed for the detection of enzymes inside cells.
Permanent Link: http://hdl.handle.net/11104/0215651