A simple device for quantitation of Caspase 3 in individual apoptotic embryonic cells

0386270 - ÚIACH 2013 RIV CZ eng C - Conference Paper (international conference)
Hegrová, Jitka - Klepárník, Karel - Přikryl, Jan - Lišková, Marcela - Matalová, Eva - Foret, František
A simple device for quantitation of Caspase 3 in individual apoptotic embryonic cells.
CECE 2012. 9th International Interdisciplinary Meeting on Bioanalysis. Brno: Ústav analytické chemie AV ČR, v. v. i, 2012 - (Foret, F.; Křenková, J.; Guttman, A.; Klepárník, K.; Boček, P.), s. 354-356. ISBN 978-80-904959-1-3.
[CECE 2012. International Interdisciplinary Meeting on Bioanalysis /9./. Brno (CZ), 01.11.2012-02.11.2012]
R&D Projects: GA ČR(CZ) GAP301/11/2055; GA ČR GAP206/11/2377; GA ČR(CZ) GPP206/11/P002
Institutional support: RVO:68081715 ; RVO:67985904
Keywords : single cell * chemiluminiscence * Caspase 3
Subject RIV: CB - Analytical Chemistry, Separation

A newly developed system for the determination of Caspase 3 activity in individual apoptotic embryonic cells is described. Caspase 3, a cysteine-aspartic acid protease activated in the apoptotic pathway, plays an essential role in the programmed cell death. Moreover, failure of apoptosis is one of the main contributions to tumor development.
Permanent Link: http://hdl.handle.net/11104/0215496