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Circular dichroism spectroscopy of nucleic acids

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    0386144 - BFÚ 2013 RIV US eng M - Monography Chapter
    Kypr, Jaroslav - Kejnovská, Iva - Bednářová, Klára - Vorlíčková, Michaela
    Comprehensive chiroptical spectroscopy. Applications in stereochemical analysis of synthetic compounds, natural products, and biomolecules.
    Circular dichroism spectroscopy of nucleic acids. New Jersey: John Wiley & Sons, 2012 - (Berova, N.; Polavarapu, P.; Nakanishi, K.; Woody, R.), s. 575-586. ISBN 978-0-470-64135-4
    R&D Projects: GA AV ČR(CZ) IAA500040903; GA AV ČR(CZ) IAA100040701
    Institutional research plan: CEZ:AV0Z50040702
    Keywords : circular dichroism * nucleic acid conformations * structural transitions
    Subject RIV: BO - Biophysics

    We review problems where CD spectroscopy contributed to the understanding of the conformational polymorphism of DNA. Circular dichroism (CD)arises from differential absorption of right handed and left handed circularly polarized light by chiral molecules. This phenomenon has been described in detail in previous books. In nucleic acids there are three sources of chirality.
    Permanent Link: http://hdl.handle.net/11104/0215390

     
     
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