Astrocytes: Structure, Functions and Role in Disease

0383198 - ÚEM 2013 RIV US eng M - Monography Chapter
Anděrová, Miroslava - Pivoňková, Helena
Astrocytic Potassium Channels in CNS Disorders.
Astrocytes: Structure, Functions and Role in Disease. New York: Nova Science Publishers, 2012 - (González-Pérez, O.), s. 17-36. ISBN 978-1-62081-585-4
Institutional research plan: CEZ:AV0Z50390512; CEZ:AV0Z50390703
Keywords : astroglia * potassium ion channels * CNS pathology
Subject RIV: FH - Neurology

The book summarizes the latest discoveries, from basic to clinical science, regarding the main roles of astrocytes under physiological and pathological circumstances. In this chapter we focus on summarizing current knowledge about the expression and functioning of K+ channels in astrocytes during the acute and chronic stages of CNS disorders, such as ischemia or epilepsy. The role of other proteins that might functionally interact with K+ channels and influence K+ buffering during CNS disorders, namely aquaporins and connexins, is also discussed.
Permanent Link: http://hdl.handle.net/11104/0007211