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Differential effects of acyclic nucleoside phosphonates on nitric oxide and cytokines in rat hepatocytes and macrophages
- 1.0379815 - ÚEM 2013 RIV NL eng J - Journal Article
Kostecká, Petra - Holý, Antonín - Farghali, H. - Zídek, Zdeněk - Kmoníčková, Eva
Differential effects of acyclic nucleoside phosphonates on nitric oxide and cytokines in rat hepatocytes and macrophages.
International Immunopharmacology. Roč. 12, č. 2 (2012), s. 342-349. ISSN 1567-5769. E-ISSN 1878-1705
R&D Projects: GA MŠMT 1M0508
Institutional research plan: CEZ:AV0Z50390512; CEZ:AV0Z40550506
Keywords : acyclic nucleoside phosphonates * cytokines * nitric oxide
Subject RIV: FR - Pharmacology ; Medidal Chemistry; CC - Organic Chemistry (UOCHB-X)
Impact factor: 2.417, year: 2012
Derivatives of antiviral acyclic nucleoside phosphonates stimulate production of nitric oxide and secretion of cytokines in parenchymal liver cells. Hepatocytes may play an active immunomodulatory role in the liver.
Permanent Link: http://hdl.handle.net/11104/0210687
Number of the records: 1