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Fate map of the dental mesenchyme: Dynamic development of the dental papilla and follicle
- 1.0379333 - ÚEM 2013 RIV US eng J - Journal Article
Rothová, Michaela - Peterková, Renata - Tucker, A. S.
Fate map of the dental mesenchyme: Dynamic development of the dental papilla and follicle.
Developmental Biology. Roč. 366, č. 2 (2012), s. 244-254. ISSN 0012-1606. E-ISSN 1095-564X
R&D Projects: GA ČR GA304/07/0223
Institutional research plan: CEZ:AV0Z50390703; CEZ:AV0Z50390512
Keywords : tooth * mouse * mesenchyme
Subject RIV: EA - Cell Biology
Impact factor: 3.868, year: 2012
At the bud stage the mesenchymal cells adjacent to the tip of the bud form both the dental papilla and dental follicle. At the early cap stage a small population of highly proliferative mesenchymal cells in close proximity to the inner dental epithelium and primary enamel knot provide the major contribution to the dental papilla. These cells are located between the cervical loops, within a region we have called the body of the enamel organ, and proliferate in concert with the epithelium to create the dental papilla. The condensed dental mesenchymal cells that are not located between the body of the enamel organ, and therefore are at a distance from the primary enamel knot, contribute to the dental follicle, and also the apical part of the papilla, where the roots will ultimately develop. Some cells in the presumptive dental papilla at the cap stage contribute to the follicle at the bell stage, indicating that the dental papilla and dental follicle are still not defined populations at this stage.
Permanent Link: http://hdl.handle.net/11104/0210571
Number of the records: 1