Detection of mosquito-only flaviviruses in Europe

0377083 - BC 2013 RIV GB eng J - Journal Article
Calzolari, M. - Zé-Zé, L. - Růžek, Daniel - Vazquez, A. - Jeffries, C. - Defilippo, F. - Osório, H.C. - Kilian, Patrik - Ruíz, S. - Fooks, A. R. - Maioli, G. - Amaro, F. - Tlustý, M. - Figuerola, J. - Medlock, J. M. - Bonilauri, P. - Alves, M. J. - Šebesta, Oldřich - Tenorio, A. - Vaux, A. G. C. - Bellini, R. - Gelbič, Ivan - Sánchez-Seco, M. P. - Johnson, N. - Dottori, M.
Detection of mosquito-only flaviviruses in Europe.
Journal of General Virology. Roč. 93, č. 6 (2012), s. 1215-1225. ISSN 0022-1317. E-ISSN 1465-2099
R&D Projects: GA MŠMT 2B08003; GA MŠMT(CZ) LC06009; GA ČR GD206/09/H026
Institutional research plan: CEZ:AV0Z60220518; CEZ:AV0Z50070508; CEZ:AV0Z60930519
Keywords : WEST-NILE-VIRUS * INSECT-SPECIFIC FLAVIVIRUSES * POLYMERASE CHAIN-REACTION * FUSING AGENT VIRUS * AEDES-ALBOPICTUS * CULEX FLAVIVIRUS * DIPTERA-CULICIDAE * PHYLOGENETIC ANALYSIS * SURVEILLANCE * TRANSMISSION
Subject RIV: EC - Immunology
Impact factor: 3.127, year: 2012
http://link.springer.com/article/10.1007%2Fs00436-012-2928-4

The genus Flavivirus, family Flaviviridae, includes a number of important arthropod-transmitted human pathogens such as dengue viruses, West Nile virus, Japanese encephalitis virus and yellow fever virus. In addition, the genus includes flaviviruses without a known vertebrate reservoir, which have been detected only in insects, particularly in mosquitoes, such as cell fusing agent virus, Kamiti River virus, Culex flavivirus, Aedes flavivirus, Quang Binh virus, Nakiwogo virus and Calbertado virus. Reports of the detection of these viruses with no recognized pathogenic role in humans are increasing in mosquitoes collected around the world, particularly in those sampled in entomological surveys targeting pathogenic flaviviruses. The presence of six potential flaviviruses, detected from independent European arbovirus surveys undertaken in the Czech Republic, Italy, Portugal, Spain and the UK between 2007 and 2010, is reported in this work. Whilst the Aedes flaviviruses, detected in Italy from Aedes albopictus mosquitoes, had already been isolated in Japan, the remaining five viruses have not been reported previously: one was detected in Italy, Portugal and Spain from Aedes mosquitoes (particularly from Aedes caspius), one in Portugal and Spain from Culex theileri mosquitoes, one in the Czech Republic and Italy from Aedes vexans, one in the Czech Republic from Aedes vexans and the last in the UK from Aedes cinereus. Phylogenetic analysis confirmed the close relationship of these putative viruses to other insectonly flaviviruses.
Permanent Link: http://hdl.handle.net/11104/0209337