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Association Between TAS2R38 Gene Polymorphisms and Colorectal Cancer Risk: A Case-Control Study in Two Independent Populations of Caucasian Origin
- 1.0375559 - ÚEM 2012 RIV US eng J - Journal Article
Carrai, M. - Steinke, V. - Vodička, Pavel - Pardini, Barbara - Rahner, N. - Holinski-Feder, E. - Morak, M. - Schackert, H. K. - Görgens, H. - Stemmler, S. - Betz, B. - Kloor, M. - Engel, C. - Büttner, R. - Naccarati, Alessio - Vodičková, Ludmila - Novotný, J. - Stein, A. - Hemminki, K. - Propping, P. - Försti, A. - Canzian, F. - Barale, R. - Campa, D.
Association Between TAS2R38 Gene Polymorphisms and Colorectal Cancer Risk: A Case-Control Study in Two Independent Populations of Caucasian Origin.
PLoS ONE. Roč. 6, č. 6 (2011), e20464. ISSN 1932-6203. E-ISSN 1932-6203
R&D Projects: GA ČR GA310/07/1430; GA MŠMT 7F10069
Institutional research plan: CEZ:AV0Z50390512
Keywords : CRC * bitter taste receptors
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 4.092, year: 2011
Taste receptors over the whole gastrointestinal tract can influence the selection and intake of the food. In the present study we investigated all the common genetic variation of one taste receptor gene in relation to colorectal cancer risk. In conclusion, we found a suggestive association between the human bitter tasting phenotype and the risk of CRC in two different populations of Caucasian origin.
Permanent Link: http://hdl.handle.net/11104/0208178
Number of the records: 1