Cancer immunology and colorectal cancer recurrence

0375273 - MBÚ 2012 RIV US eng J - Journal Article
Vannucci, Luca
Cancer immunology and colorectal cancer recurrence.
Frontiers in Bioscience (Scholar Edition). -, č. 3 (2011), s. 1421-1431. ISSN 1945-0524
R&D Projects: GA AV ČR IAA500200917
Institutional research plan: CEZ:AV0Z50200510
Keywords : colorectal cancer * inflammation * tumor
Subject RIV: EC - Immunology

The recurrence of a cancer - local or distant (metastasis) - is manifested by the persistence of cancer cells in the organism after the ablation of the primary lesion, an ineffective anticancer immune response, and by the activity of biological/immunological factors that can stimulate and sustain its development. This review focuses on colorectal carcinoma and discusses some aspects of cancer immunology regarding cancer development and its recurrence. It is addressed also to the clinician to provide new insights helpful for designing better therapeutic strategies and patient's follow up. Therapeutic approaches used during and after surgical treatments, found capable of modulating immunity (differently affecting disease outcome), will also be described
Permanent Link: http://hdl.handle.net/11104/0207975