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Method of making arranged cell structures

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    0375168 - FZÚ 2012 RIV eng P - Patent Document
    Rezek, Bohuslav - Michalíková, L. - Kromka, Alexander - Kalbáčová, M. - Kmoch, S. - Grausová, Ľubica - Bačáková, Lucie - Vaněček, Milan - Kočka, Jan
    Method of making arranged cell structures.
    2011. Owner: Fyzikální ústav AV ČR, v. v. i. - Fyziologický ústav AV ČR, v. v. i. - Univerzita Karlova. Date of the patent acceptance: 28.12.2011. Patent Number: EP2288699
    R&D Projects: GA AV ČR KAN400100701; GA MŠMT LC510; GA AV ČR(CZ) IAAX00100902
    Institutional research plan: CEZ:AV0Z10100521; CEZ:AV0Z50110509
    Keywords : biology * diamond * cell arrays * biomaterials * biointerfaces * bioelectronics
    Subject RIV: BM - Solid Matter Physics ; Magnetism
    https://data.epo.org/publication-server/pdf-document?pn=2288699&ki=B1&cc=EP

    Way of fabricating ordered cell structures is specific by the procedure that hydrogen- and oxygen- terminated regions are generated on a diamond surface by plasma discharge and such diamond is immersed into the medium containing human-like cells. The cells, that are able to create bone or neuronal tissue, selectively colonize oxygen-terminated (hydrophilic) diamond surface. Crucial parameter is initial concentration of cells and of fetal bovine serum in the medium. Diamond can be also morphologically structured. Diamond can be natural or synthetic on arbitrary substrate. Concentration of dopants in diamond is not limited.
    Permanent Link: http://hdl.handle.net/11104/0207900

     
     
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