Superparamagnitnye nanochastitsy na osnove oksidov zheleza s modifitsirovannoj poverkhnostyu, sposob ikh polucheniya i primenenie

0373388 - ÚMCH 2012 RIV rus P - Patent Document
Horák, Daniel - Syková, Eva - Babič, Michal - Jendelová, Pavla - Hájek, Milan
Superparamagnitnye nanochastitsy na osnove oksidov zheleza s modifitsirovannoj poverkhnostyu, sposob ikh polucheniya i primenenie.
[Iron oxide-based superparamagnetic nanoparticles with modified surface, process of their preparation and use.]
2011. Owner: Ústav makromolekulární chemie AV ČR, v. v. i. - Ústav experimentální medicíny AV ČR, v. v. i. Date of the patent acceptance: 31.10.2011. Patent Number: EA015718
R&D Projects: GA ČR GA203/09/1242; GA MŠMT 1M0538
Institutional research plan: CEZ:AV0Z40500505; CEZ:AV0Z50390512
Keywords : superparamagnetic * nanoparticles * cell labeling
Subject RIV: CD - Macromolecular Chemistry
http://www.eapatis.com/ruSearch/ms.exeData/EAPO/EAPO2011/PDF/015718.PDF

V nastoyashchyee izobretenie raskryvaetsya superparamagnitnykh nanochastits zondov na osnove oksidov zheleza, predpochtitelno magnetita ili maggemita s modifitsirovannoj poverkhnostyu , otlichayushchijsya tem, chto oni pokryty s mono -, di- ili polisakharidov vybran iz gruppy, sostoyashchyej iz D- arabinozy, D- glyukozy , D- galaktozy , D- mannozy, laktozy, maltozy, dekstranov i dekstrinov ili aminokislot ili poli ( aminokisloty) s iz gruppy, vklyuchayushchyej alanin , glitsin, glutamin , asparagin, gistidin, arginin , L lizina , asparaginovoj i glutaminovoj kisloty i obrazuyut kolloidnyj , sostoyashchij iz chastits.

In the present invention, there are disclosed superparamagnetic nanoparticle probes based on iron oxides, preferably magnetite or maghemite, with modified surface, characterized in that they are coated with mono-, di- or polysaccharides being selected from the group consisting of D-arabinose, D-glucose, D-galactose, D-mannose, lactose, maltose, dextrans and dextrins or amino acids or poly(amino acid)s from the group including alanine, glycine, glutamine, asparagine, histidine, arginine, L lysine, aspartic and glutamic acid, and form a colloid consisting of particles.
Permanent Link: http://hdl.handle.net/11104/0206497