Emerging subject for chiral separation science: cluster boron compounds

0372091 - ÚACH 2012 RIV US eng J - Journal Article
Horáková, H. - Grüner, Bohumír - Vespalec, R.
Emerging subject for chiral separation science: cluster boron compounds.
Chirality. Roč. 23, č. 4 (2011), s. 307-319. ISSN 0899-0042. E-ISSN 1520-636X
R&D Projects: GA AV ČR IAA400310613
Institutional research plan: CEZ:AV0Z40320502
Keywords : chiral separations * boranes * carboranes * lliquid chromatography * capillary electrophoresis * cyclodextrins
Subject RIV: CA - Inorganic Chemistry
Impact factor: 2.350, year: 2011

The structural chirality is an inherent feature of fully synthetic boron cluster compounds that sometimes exhibit unique biochemical effects. HPLC studies with zwitter-ionic cluster boron compounds and electrophoretic studies with boron cluster anions reveal that the chiral separability of these species is remarkably dissimilar to that of organic species, if uncharged cyclodextrins are used as chiral selectors. Furthermore, marked differences were found between the analytical characteristics of the chiral separations of the boron cluster species and those of the organic species with uncharged cyclodextrins. The present-day experimental database indicates that the rules valid for the chiral separations of the organic species cannot be applied to the chiral separations of the boron cluster species without experimental verification. The current extent of research work devoted to the investigation of chirality and chiral separations of boron cluster species is negligibly small in comparison with that devoted to the investigation of chirality and chiral separations of organic species.
Permanent Link: http://hdl.handle.net/11104/0205482