The evolution of rectal and urinary toxicity and immune response in prostate cancer patients treated with two three-dimensional conformal radiotherapy techniques

0370654 - MBÚ 2012 RIV GB eng J - Journal Article
Vránová, J. - Vinakurau, S. - Richter, J. - Starec, M. - Fišerová, Anna - Rosina, J.
The evolution of rectal and urinary toxicity and immune response in prostate cancer patients treated with two three-dimensional conformal radiotherapy techniques.
Radiation Oncology. Roč. 2, č. 6 (2011), s. 1-13. E-ISSN 1748-717X
R&D Projects: GA AV ČR IAA500200620
Institutional research plan: CEZ:AV0Z50200510
Keywords : 3-dimensional conformal radiotherapy (3DCRT) * gastrointestinal and genitourinary toxicity * prostate cancer
Subject RIV: EC - Immunology
Impact factor: 2.321, year: 2011

Our research compared whole pelvic (WP) and prostate-only (PO) 3-dimensional conformal radiotherapy (3DCRT) techniques in terms of the incidence and evolution of acute and late toxicity of the rectum and urinary bladder, and identified the PTV-parameters influencing these damages and changes in antitumor immune response. Our study demonstrates the association of acute and late damage of the urinary bladder and rectum, with clinical and treatment related factors
Permanent Link: http://hdl.handle.net/11104/0204384