Different charged short lipopeptides

0370541 - ÚOCHB 2012 CZ eng C - Conference Paper (international conference)
Ježek, R. - Slaninová, Jiřina - Králová, M. - Macková, M.
Different charged short lipopeptides.
Biologically Active Peptides. 12th Conference. Praha: Institute of Organic Chemistry and Biochemistry AS CR, v. v. i, 2011 - (Slaninová, J.), s. 51-53. Collection Symposium Series, 13. ISBN 978-80-86241-44-9.
[Biologically Active Peptides /12./. Praha (CZ), 27.04.2011-29.04.2011]
R&D Projects: GA ČR GA203/08/0536
Grant - others:GA ČR(CZ) GA522/09/1693
Program: GA
Institutional research plan: CEZ:AV0Z40550506
Keywords : peptide synthesis * antimicrobial activity * palmitoylation
Subject RIV: CC - Organic Chemistry

Series of short peptides palmitoylated in different positions was designed, synthesized and tested for antimicrobial activities. The palmitoyl group was situated either on the alpha - amino group in position 1 or on the epsilon - amino group of lysine in position 3. The peptide charge ranged from –3 to +4. The peptide part of the lipopeptides constituted mainly from lysine, arginine and glutamic acid.
Permanent Link: http://hdl.handle.net/11104/0204325