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Osmium tetroxide complexes as versatile tools for structure probing and electrochemical analysis of biopolymers
- 1.0370536 - BFÚ 2012 RIV US eng J - Journal Article
Fojta, Miroslav - Kostečka, Pavel - Pivoňková, Hana - Horáková Brázdilová, Petra - Havran, Luděk
Osmium tetroxide complexes as versatile tools for structure probing and electrochemical analysis of biopolymers.
Current Analytical Chemistry. Roč. 7, č. 1 (2011), s. 35-50. ISSN 1573-4110. E-ISSN 1875-6727
R&D Projects: GA AV ČR(CZ) IAA400040901; GA AV ČR(CZ) IAA400040903; GA ČR(CZ) GP203/08/P598; GA MŠMT(CZ) LC06035
Institutional research plan: CEZ:AV0Z50040507; CEZ:AV0Z50040702
Keywords : osmium complexes * DNA labelling * electrochemical analysis
Subject RIV: BO - Biophysics
Impact factor: 1.000, year: 2011
Osmium tetroxide complexes with nitrogenous ligands and analogous six-valent osmium proved excellent tools for selective labeling of biopolymers. Utilization of the osmium tags in probing DNA structural transitions, sensing of DNA hybridization, damage and DNA methylation, labeling of peptides and proteins, probing accessibility of tryptophan residues in proteins and their complexes, and labeling of sugar moieties, are reviewed.
Permanent Link: http://hdl.handle.net/11104/0204321
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